And, socioeconomic, psychosocial (issues like family problems, depression and sexual abuse) and physical health factors generally may disproportionately affect Black individuals, the investigators write. The findings likely indicate that cognitive tests assess different ethnic groups differently. Seventy-five percent of Black participants and 23.4% of white participants met criteria for mild cognitive impairment. Black participants were generally disproportionately affected, the investigators say. They were an average of 44.6 years old, nearly 40% were Black and 7% had been hospitalized because of COVID-19. The first enrollees were largely female - only 35.5% were male. On the other hand, cognitive testing may overestimate impairment in disadvantaged populations, they report. Many earlier reports have been based on these kinds of self-reports, and the discrepancies they are finding indicate that approach may not reflect objective dysfunction, the investigators write. Others, for example, may rely on these senses more, even when they are preparing the food, and may be apt to notice even a slight change, she says.Įither way, their data and others suggest a persistent loss of taste and smell following COVID-19, Rutkowski and her colleagues write. “They eat a chicken sandwich and it tastes like smoke or candles or some weird other thing, but our taste strips are trying to depict specific tastes like salty and sweet,” Rutkowski says.
While the reasons are not certain, part of the discrepancy may be a change in the quality of their taste and smell rather than pure impaired ability, Rutkowski says. In fact, a higher percentage of those who did not report the changes actually had evidence of impaired function based on objective measures, the investigators write. And, it was bidirectional.įor example, the majority of participants reported taste and smell changes, but objective testing of both these senses did not always line up with what they reported. While the findings to date are not surprising and are consistent with what other investigators are finding, Rutkowski says the fact that symptoms reported by participants often didn’t match what objective testing indicated was surprising. Anemia and a history of depression were associated with the 18% who met the objective criteria for anxiety. Twenty-five percent met the criteria for depression, and diabetes, obesity, sleep apnea and a history of depression were associated with those who met the criteria. No participants reported having a stroke, weakness or inability to control muscles involved with speaking, and coordination problems were some of the less frequently reported symptoms. Twenty-one percent reported confusion, and hypertension was the most common medical condition reported by participants in addition to their bout with COVID-19. Just over half reported changes in smell (54.5%) and taste (54%) and nearly half the participants (47%) met the criteria for mild cognitive impairment, with 30% demonstrating impaired vocabulary and 32% having impaired working memory.
The published study reports on preliminary findings from the first visit of the first 200 patients enrolled in the COVID-19 Neurological and Molecular Prospective Cohort Study in Georgia, or CONGA, who were recruited on average about 125 days after testing positive for the COVID-19 virus.ĬONGA was established at MCG early in the pandemic in 2020 to examine the severity and longevity of neurological problems and began enrolling participants in March 2020 with the ultimate goal of recruiting 500 over five years.Įighty percent of the first 200 participants reported neurological symptoms with fatigue, the most common symptom, reported by 68.5%, and headache close behind at 66.5%. Elizabeth Rutkowski, MCG neurologist and the study’s corresponding author.
“There are a lot of symptoms that we did not know early on in the pandemic what to make of them, but now it’s clear there is a long COVID syndrome and that a lot of people are affected,” says Dr. “Our results support the growing evidence that there are chronic neuropsychiatric symptoms following COVID-19 infections,” Medical College of Georgia investigators write in the journal ScienceDirect. Muscle aches, cough, changes in smell and taste, fever, chills and nasal congestion were next in the long line of lingering symptoms. Fatigue and headache were the most common symptoms reported by individuals an average of more than four months out from having COVID-19, investigators report.
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